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    Architecting biotech ventures
    from lab to deal.

    Building equity stories. Securing capital. Driving pharma deals.
    Strategic advisory for biotech founders and investors.

    VENTURE BUILDING

    From discovery to deal. Find where you are.

    Most scientific discoveries never become companies. Most companies never close a round. Most assets never reach a pharma deal. The gap is always the same: the wrong architecture underneath the story.

    Each stage builds the next — but you can enter at any point.

    From lab to venture

    Does this discovery have the architecture of an investable asset? Start here before the business plan.

    Explore Lab to Venture →

    From story to capital

    Pitch deck audit, VC preparation, EIC Accelerator positioning. Close the gap between a good company and a funded one.

    Explore Fundraising →

    From asset to pharma deal

    Strategic business development for licensing or exit. I bridge the gap between clinical milestones and pharmaceutical boardrooms to secure high-value transactions.

    Explore Pharma Deal →

    Italy Gateway

    Italy is not a secondary market. It is the entry point.

    Italy's IRCCS network offers a distinctive institutional model: over 50 research hospitals where clinical care and scientific research operate under the same roof, in the disease areas where diagnostics innovation matters most. Structuring the right partnerships within this network is the strategic groundwork that determines whether your European market entry starts strong or stalls. The complexity is real. So is the opportunity.

    See the Italy Gateway →

    Clinical evidence strategy

    Italy's IRCCS research hospitals combine clinical care with mandated scientific research. Mapping the right institutional partners, the right disease focus, and the right study design is the strategic work that comes before the regulatory execution.

    IRCCS network and clinical partnerships

    Not all of the over 50 IRCCS are equivalent. Identifying the institutions with the right research infrastructure, the right investigators, and the right disease focus for your product is a strategic decision that shapes everything downstream.

    Market entry architecture

    Regulatory pathway, clinical partnerships, regional dynamics, procurement logic: an Italian market entry has moving parts that must be assembled in the right sequence. The strategic architecture comes first. The specialist execution follows.

    Leonardo Biondi

    Leonardo Biondi

    Biotech Venture Architect · Lecturer, Università Vita-Salute San Raffaele

    20 years at the intersection of science, capital, and cross-border deals. I am not a scientist. That is why I ask the questions that matter.

    InsightsAll articles
    equity story

    The equity story is not a pitch. It is a thesis.

    Most founders confuse the pitch with the equity story. A pitch sells. An equity story structures the logic of value creation so that every investor, board member, and pharma partner sees the same architecture.

    12 min read
    Read article →
    venture building

    What is a venture architect in biotech and what do they do?

    fundraising

    How to fund a biotech startup in Europe: the guide

    market entry

    For oncology diagnostics, Italy is the logical first market in Europe

    investor readiness

    How to translate preclinical data into investor language

    All insights →

    Worth reading. Worth keeping.

    Strategic notes on biotech fundraising and venture design. When there is something worth saying. No filler, no cadence for its own sake. Unsubscribe anytime.

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    In their words

    Heard in the room.

    Bridges scientific research and practical applications. Helped establish joint labs across Asia — including labs at NCBS/inStem — a strong model for international collaboration.”

    K. VijayRaghavan

    Professor Emeritus, NCBS; former Principal Scientific Adviser to the Government of India.

    “Very competent in collaboration agreements and negotiations… created a strong bridge between researchers in Japan and Italy.”

    Piero Carninci

    Head, Genomics Research Center, Human Technopole; President, HUGO (2025–2027).

    “A fantastic team player and natural leader who bridges science and business in pharma/biotech.”

    Francesco Grillo

    Start-up & Portfolio Manager, Max Planck Innovation.

    “An exceptionally capable and analytical manager with a deep understanding of the biotech and venture capital industry.”

    Jacopo Franchini

    Strategic Marketing Advisor, Recordati Rare Diseases.

    The gap between your science and its market will not close itself.

    30 minutes. No pitch. An honest conversation about where you are and what the next move is.

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